The Correlation Between Heart Disease and Hot Flashes

8 min read

Medically reviewed by :
Dr. Kay Chandler
OBGYN/ FACOG
March 16, 2025

Little-Known Correlation

At a routine OB/GYN appointment, you mention the frustration of recurring hot flashes, and your doctor responds, "They are annoying, but they’ll pass soon. Menopause symptoms are harmless anyway."

Unfortunately, this is a false statement. Misunderstandings like these are why over 70% of women seeking hormonal help leave without a prescription. This often leads to feelings of hopelessness and frustration, a common experience for many women.

Hot flashes are the most common symptom of menopause, with approximately 80% of women experiencing them. According to the Mayo Clinic, “On average, hot flash symptoms persist for more than seven years. Some women experience them for more than 10 years.” [1].

The Truth Revealed

  • Hot flashes can last for years and, in some cases, for more than a decade.
  • Bioidentical Hormone Replacement Therapy (BHRT) at therapeutic levels can mitigate or stop hot flashes.
  • There is a strong connection between hot flashes and heart disease, the leading cause of death for women globally.

A 2019 study published by Everyday Health noted that women typically develop heart disease about 10 years later in life than men. However, research published in 2020 highlighted how menopause elevates a woman’s risk for cardiovascular disease (CVD) [2].

A more recent study from Menopause (December 2022) examined the relationship between menopausal symptoms, including hot flashes, and long-term heart disease. It involved over 80,000 postmenopausal women, focusing on symptoms like night sweats, joint pain, racing heart, dizziness, mood swings, and difficulty concentrating. None of the participants had CVD before menopause. The study found that women with persistent or severe hot flashes had a significantly higher likelihood of developing cardiovascular disease.

Hot flashes are triggered by the hypothalamus, the brain's temperature regulator. When estrogen drops during menopause, it disrupts the balance with another chemical, NKB, causing the hypothalamus to raise body temperature, leading to hot flashes. This imbalance and the resulting temperature changes appear to correlate with an increased risk of heart disease. More research is needed to determine if hot flashes cause heart disease or simply indicate a failing cardiovascular system.

Is There Any Good News? YES!

BHRT, when administered at therapeutic levels, can significantly reduce or eliminate menopausal symptoms. While many BHRT programs provide a measure of hormonal help, they may not provide adequate support for core body systems.

Hormones play a key role in maintaining strong bones, a healthy cardiovascular system, and balanced brain chemistry. Keeping hormones at physiological levels helps the body function optimally. Studies show that restoring hormone levels can:

  • Remineralizer bones
  • Restore blood vessel health and reduce cardiovascular plaque
  • Strengthen the skeletal system, reducing the risk of osteoporosis
  • Enhance brain signal transmission, potentially improving cognitive function

Can I Reduce My Risk of Heart Disease?

While certain health risks are genetic, others can be modified. You can’t change your age or genetics, but maintaining a healthy diet, exercising, and managing stress can significantly reduce your risk factors. Additionally, BHRT can replenish hormones that your body once produced, improving overall health.

Several recent studies have shown a clear link between hot flashes and an increased risk of heart attack and stroke. In fact, women experiencing frequent hot flashes have a 75% higher chance of cardiovascular disease over the next two decades [3].

Newer research indicates that starting BHRT by age 60 can significantly reduce heart disease risk.

Summary

Persistent and severe hot flashes are linked to an increased risk of heart disease. With heart disease being a leading cause of death in women, it is crucial to mitigate this risk. BHRT can significantly reduce not only the risk of cardiovascular disease but also other menopause-related conditions such as osteoporosis and cognitive decline. Furthermore, BHRT can improve mood, sleep, skin, and even libido.

Sources

  1. Mayo Clinic: "Hot Flashes"
  2. Everyday Health: "Severe Menopause Symptoms Linked to Risk of Heart Disease"
  3. Bansal, Ramandeep. “Menopausal Hot Flashes: A Concise Review.” Journal of Midlife Health, vol. 10, no. 1, 2019, pp. 6-13.
  4. Glenn, Katie. “Hormone Replacement Therapy Associated with Lower Mortality.” American College of Cardiology. Link
  5. International Journal of Environmental Research and Public Health. Mark Woodward. "Cardiovascular Disease and the Female Disadvantage," April 16, 2019. NIH
  6. Women's Health: Menopause